Episode 23 - Adrenal Glands

The amazing adrenal glands produce and release important hormones involved in the stress response of organisms. This includes adrenaline (epinephrine), glucocorticoids (cortisol), sex hormones (androgens), and mineralocorticoids (aldosterone).

Episode 21 - Endocrine System (Hypothalamus & Pituitary)

In this episode we explore the anatomy and physiology of the hypothalamus and pituitary gland. We describe the hormones produced by each and what they do! We also talk about certain diseases that can arise from having either too much or not enough of these hormones!
We talk about oxytocin, vasopressin (ADH), growth hormone, prolactin, adrenocorticotropic hormone, thyroid stimulating hormone, follicle stimulating hormone, and leutenizing hormone! So many!!!!

Episode 20 - Cranial nerves and how to test them!

In Episode 20, Dr. Matt & Dr. Mike go through the 12 pairs of cranial nerves!
They explain how to remember their names! How to remember whether they are sensory, motor, or both! AND how to test them clinically!!

Episode 19 - Autonomic Nervous System (Parasympathetic & Sympathetic Divisions))

Here we introduce the anatomy, physiology, and pharmacology of the autonomic nervous system. After finding out what Dr Matt did in India, we explore why we have a sympathetic (fight or flight) and parasympathetic (rest and digest) division of the nervous system. We look at cholinergic receptors and adrenergic receptors and where they are located. And finally, what drugs can do to alter these systems - enjoy!!

Episode 18 - The Brain! Including lobes, corpus callosum, and cerebellum!

Wow! This episode has some great facts and information! Such as:
- Brain metabolism (sugar, lactate, and ketones)
- Frontal lobe (Phineas Gage getting a rod through his head, motor cortex, dementia, and Broca's aphasia - inability to create words)
- Parietal lobe (Sensory cortex, phantom limb, neuroplasticity, disowning your own body parts)
- Temporal lobe (memory, learning, epilepsy and religious experiences, Wernicke's aphasia - word-salad)
- Occpital lobe (interpreting vision, visual disorders)
- Insula (food avoidance after food poisoning)
- Corpus Callosum (Split brain experiment, separating consciousness, confabulation)
- Cerebellum (proprioception, balance, cerebral ataxia, walking on all four limbs, getting drunk)

Episode 17 - Resting Membrane & Action Potential (Clinical relevance!!)

In order for our neurons to fire off, heart muscle to contract, and kidneys to reabsorb substances, the cells in our body need to establish charge and concentration differences between the inside of the cell and outside the cell (resting membrane potential). In this episode, we explore how our body creates these differences and exploit them to send signals to and from the brain (action potential). We also discuss what can happen to the body if we alter these concentrations and charges.

Episode 16 - The Nervous System (An introduction)

In this episode Dr. Matt and Dr. Mike introduce the nervous system. They outline the various components of the central nervous system (brain and spinal cord) and peripheral nervous system (cranial nerves and spinal nerves)  and discuss its primary functions. Dr. Matt also explains to Dr. Mike the embryological development of the nervous system.

Episode 15 - Arterial Blood Gas (ABG) analysis

"ABGs are easy as 1,2,3!!"
In this episode Dr Matt and Dr Mike explain how to read an arterial blood gas (ABG) report and help determine whether a patient has a respiratory or metabolic based acidosis or alkalosis. They also look at some complex mixed cases and explain some easy ways to determine what's going on?!

Episode 14 - Acid Base Physiology

Did you know that you can change the pH of your blood by breathing? In this episode Dr. Matt and Dr. Mike explore the differences between acidosis and alkalosis. What is pH? What is an acid? What is a base? Clinically, why are we so concerned about the concentration of hydrogen ions (H+)??

Episode 13 - Lactation and Breastfeeding

Dr. Mike has recently had a baby and is experiencing the complexities of breastfeeding. In this episode Dr Matt & Dr Mike discuss the anatomy and physiology of lactation. They are also joined by a special guest, Midwife & Nurse, Rose Townley, to discuss the complexities of breastfeeding for both mum and bub.  

Episode 11 - The Glomerulus & Glomerular filtration rate

The Glomerulus (meaning ball of yarn) is a capillary network in the kidneys that decides what gets filtered from the blood into urine.Our kidneys need to filter 120mL per minute (or 180L per day) of blood in order to maintain the appropriate amount of salts, pH, waste, and other components in the blood. If this membrane is damaged or disrupted, patient health can rapidly decline.
What is the glomerulus? How does it work? How can it be damaged? What are some diseases of the glomerulus?

Episode 10 - Renin Angiotensin Aldosterone System (RAAS)

Did you know that our kidneys control our blood pressure? It does this so it can continually create 180 litres of filtered blood every day to keep us healthy!
The system that the kidneys use to control blood pressure is called the renin angiotensin aldosterone system (RAAS) - it's a big name but easy to learn!
Many patients with hypertension manage their blood pressure by taking medications that act upon this system!
Join Dr. Matt & Dr. Mike in this episode to explore this clinically important system!